Capsule Machines

ProFiller® 1100

Hand-Held Capsule Filling System

• Hand-Held Filler Base, Orienter Base, and Locking Plate

• Change Parts for one capsule size

• Tamper

• Powder Spreader

• Powder Tray

• Powder Tray Clamps

• Change parts available for additional capsule sizes

Easier to Use

• Multiple design features make it easier to use than other hand-held systems.

• Fill powder using tapping, tamping, or vibration (optional).

• Inox (Stainless Steel 316) plates for reduced static.

• Includes a Capsule Locker for hard-to-lock powders.

Faster Size Changes & Cleaning

• High GMP, all metal parts are Inox (Stainless Steel 316).

• Change capsule sizes in 2 minutes. Change Parts available in sizes 00-4 for all systems. Order 1100 for 000, 5, 00el- 2el.

• Size changes are adjustment and tool-free.

• All parts are dishwasher safe & can be dried in a hot air oven or with a portable hair dryer.

• Designed for fast disassembly & visual verification of cleaning.

Pharmacopoeia Compliant

• Fill weights, USP/EP method within ± 1-2% of average.

• Validation package available for cGMP compliance.

• Works with all capsules including gelatin, vegetarian, & starch capsules.

Higher Output

• Up to 35% faster than other systems based on a patented design & included accessories.

• Tamper size range optimized for higher fill weights and faster filling.

• Unique features include lightweight Orienter, Orienter locator, and extra deep Powder Tray & Powder Tray clamps.

• Fully lock capsules after filling, unlike other hand-held fillers saving you time and frustration!

Automatic Dishwasher All parts fully dishwasher safe using automatic dishwasher detergents. Place plastic parts in top rack (<70°C / 160°F).
Cleaning Agents Recommend cleaning using household hand dishwashing liquid. All parts may be cleaned with NaOH (caustic soda) 1-2% solution, 1% sodium thiosulphate solution, or liquid detergents with up to 4% sodium hypochlorite. Rinse thoroughly.
Isopropyl Alcohol Wipe parts with a cloth dipped in isopropyl alcohol, then immediately wipe dry with a clean cloth. Do not use on acrylic Capsule Locker or acrylic Orienter Base (1060 & 1120). Acrylic parts can be cleaned with a solution of 15% Ethyl Alcohol (Ethanol) and 85% water. Wipe parts with a cloth dipped in ethanol solution, then immediately wipe dry with a clean cloth.
Hot Air Drying Up to 60° C. Remove plastic parts from oven after 15-20 minutes. Keep portable hair dryer at a distance of 12 inches (30 cm) from all items.
Autoclave Do not autoclave plastic parts. Other parts may be autoclaved at 121°C, 15 psi pressure for 15 minutes. For ProFiller 1100, plastic parts are available in autoclavable metals in the P10 AK Autoclave Kit in Accessories.
Maintenance Kit

Includes 1 cleaning brush, 1 nylon cleaning pad, 2 Filler Base feet, 2 Orienter Base screws, and 2 Spacer Plate feet for each size

Tamper 100-Pin

For Faster Filling

Partial Batch Kit

Fill fewer than 100 capsules per batch. Includes Orienter Divider, Powder Tray Divider, and 5-pin Tamper

Bottom Plate Adjustable

• Lower capsule bodies by up to 2mm to increase fill weight by 10-15% for many powders and 2-4% for coarse or granulated powders that do not compress

• Raise capsule bodies by 0.3-0.5mm to be even with filler top sheet

Tamper 5-Pin

Each side of the Tamper is for a different capsule size range

P10 Autoclave Kit

Make the entire ProFiller 1100 autoclavable. Includes Inox (SS316) or hard anodized aluminum versions of all plastic parts, Teflon spreader, and P10 BPA.

Tap Densimeter

Used to determine tapped density for capsule filling. Eliminates calculation errors as volume is 1 ml.

P10 Liquid Fill Locking Plate

Prevents leakage between cap and body during the locking step for capsules filled with non-aqueous liquids.

ProFiller® 3600

Hand-Held Capsule Filling System

• Hand-Held Filler Base, Orienter Base

• Change Parts for one capsule size

• 60-pin Tamper

• Locking Plate

• Capsule Locker

• Powder Tray

• Powder Tray Clamps

• Push Plate

• Powder Spreaders

• Measuring Bowls

• Storage Boxes

• Capsule Bins

• Change parts available for additional capsule sizes

Easier to Use

• Easier to use than other 200 or 300 hole systems.

• Indicator gauges to assist in capsule orientation, separation, and locking.

• Fits under powder hoods and in glove boxes.

Faster Size Changes & Cleaning

• Change capsule sizes in only 5 minutes. Change Parts available for Size 000-4 and 00el-2el.

• All parts are dishwasher safe & can be dried in a hot air oven or with a portable hair dryer.

• Designed for fast disassembly & visual verification of cleaning.

Pharmacopoeia & GMP Compliant

• Fill weights, USP/EP method within ± 1-3% of average.

• All metal parts Inox (Stainless Steel 316) for less static and improved GMP.

• Validation package available for cGMP compliance.

• Works with all capsules including gelatin, vegetarian, & starch capsules.

Higher Output

• Fully lock capsules after filling, unlike other hand-held fillers saving you time and frustration!

• Inox (Stainless Steel 316) plates for reduced static.

• Tamper size range optimized for higher fill weights and faster filling. Optional 300-pin Tamper.

• Unique features include lightweight 2-piece Orienter, Orienter locator, Push Plate, and extra deep Powder Tray.

Compatible with Bench-top Filler

• The 3600 grows with your requirements. Get the 3700 Bench-top Filler for larger batches and use the same Change Parts and Orienter purchased for the 3600.

• Continue to use the 3600 Filler Base for smaller batches or production under a powder hood or in a glove box.

• Add a Vibrator at any time.

Automatic Dishwasher All parts fully dishwasher safe using automatic dishwasher detergents. Place plastic parts in top rack (<70°C / 160°F).
Cleaning Agents Recommend cleaning using household hand dishwashing liquid. All parts may be cleaned with NaOH (caustic soda) 1-2% solution, 1% sodium thiosulphate solution, or liquid detergents with up to 4% sodium hypochlorite.
Isopropyl Alcohol Wipe with a cloth dipped in isopropyl alcohol, then immediately wipe dry with a clean cloth. Do not use on Orienter Base, Locking Plate, or Capsule Locker.
Hot Air Drying Up to 60° C (140°F). Remove plastic parts from oven after 15-20 minutes. Keep portable hair dryer at a distance of 12 inches (30 cm) from all items.
Autoclave Do not autoclave Orienter Base, Locking Plate, Powder Tray, Spacer Plate, Powder Spreader, or Capsule Locker. Other parts may be autoclaved at 121°C, 15 psi pressure for 15 minutes.
Partial Batch Kit

Fill fewer than 300 capsules per batch. Includes Orienter Divider, Powder Tray Divider & Mini Powder Spreader. Order 30-pin Tamper separately.

Caps Tray

Purchase an additional Caps Tray. Note: Lightweight Anodized Aluminum Caps Tray is not Dishwasher Safe.

30-Pin Tamper

For use with ProFiller 3600 Partial Batch Kit. Tamper in Sizes 00, 0-1, 2-3, 4.

Adjustable Height Bottom Plate

Increases fill weight by lowering capsule bodies. Lowering capsule bodies by 2 mm increases fill weight for many powders by 10-15% and for coarse or granulated powers that do not compress by 2-4%.

300-Pin Tamper

For faster tamping. Tamper is 5-6 lbs (2.5-2.8 kg) and generally gives the same fill weight as the 60 pin tamper. Includes self-standing handle. Available in Sizes 00, 0-1, 2-3, 4. *180-pin tamper for 000-00el.

Tap Densimeter

Used to determine tapped density for capsule filling. Eliminates calculation errors as volume is 1 ml.

Capsule Counters

Divide your batch of capsules into 3 groups of 100 capsules, 5 groups of 60 or 10 groups of 30. Anodized Aluminum.

Over-Encapsulation Attachments

Accessories available for Tablet, Capsule, or Caplet Over-Encapsulation

ProFiller® 3700

Bench-Top Capsule Filling System

• Filler Base and Orienter Base

• Change Parts for one capsule size

• 300-pin Tamper

• Powder Tray

• Push Plate

• Powder Spreaders

• Storage Box for Loose Parts

• Measuring Bowls

• Capsule Bins

• Change parts available for additional capsule sizes

Easier to Use

• Easier to use than other 200 or 300 hole systems.

• Indicator gauges to assist in capsule orientation, separation, and locking.

• Shipped fully assembled. Ready for use in less than 1 hour.

Higher Output

• Unique features include lightweight, 2-piece Orienter (3700), Orienter locater and oversize Powder Tray & Push Plate.

• Tamper size range optimized for higher fill weights and faster filling.

• Adjustable capsule body height to make over-filling easier & faster.

Pharmacopoeia Compliant

• Fill weights, USP/EP method within ± 1-3% of average. Typically all 300 capsules/batch are within ± 4-7% of target.

• Validation package available for cGMP compliance.

• Works with all capsules including gelatin, vegetarian/HPMC, & starch capsules.

Grows With You

• Add a Vibrator at any time.

• Change Parts for 3700 in Size 000-5, 00el-2el & AAA-D; for 3800 in Size 00-4.

• Order Filler without a Tamper for vibration only operation or in a lower height configuration for use under smaller powder hoods.

GMP & Faster Clean-Out

• Dishwasher safe Inox (SS316) powder contact parts.

• Designed for fast disassembly & visual verification of cleaning.

• Filler base in lightweight, corrosion resistant anodized aluminum or upgrade to optional Inox (SS316).

• Filler’s gear, cam and optional Vibrator are fully covered.

Powder Tray with Clamps

For very fine powders. Four built-in clamps secure Powder Tray to Filler, reducing powder loss under Powder Tray. Useful when working with controlled substances (narcotics).

Capsule Locking Plate & Capsule Locker

For fully locking capsules with coarse or sticky powders e.g. salt, dolomite, frankincense, charcoal. Capsule Locking Plate is common for sizes 00-4. Both Locker & Locking Plate are required. Capsule Locker is size specific and locks 50 capsules at a time.

Lifting Handle Extension

Attaches to Lifting Handle to make capsule separation and locking under a powder hood easier.

Partial Batch Kit

Fill fewer than 300 capsules per batch. Includes 1 each of Orienter Divider, Powder Tray Divider & Mini Powder Spreader. Order 30-pin Tamper separately.

Over Fill (OF) Parts

Standard change parts allow capsules bodies to be lowered by 2mm (Size 00 by 1.2mm) below the surface of the filler. OF Change Parts allow lowering by an additional 2 mm for twice the overfill capacity (3X for Size 00).

30-pin Tamper

For use with ProFiller 3700 Partial Batch Kit. Tamper in Sizes 00, 0-1, 2-3, 4.

Capsule Counters

Divide your batch of capsules into 3 groups of 100 capsules, 5 groups of 60 or 10 groups of 30. Anodized Aluminum.

Caps Tray for 3700

Purchase an additional Caps Tray *Light-weight anodized aluminum Caps Tray is not Dishwasher Safe.

Tablet Fill Attachment

Over-encapsulate round tablets 6.0-7.3 mm diameter and 2.0-3.5 mm height. None P3X ATF STD $600 For round tablets outside the size range listed above, order a custom TFA (delivery 4-6 weeks).

Caplet Fill Attachment

For caplets or non-round tablets. Engineering drawing of tablet required. Delivery 4-8 weeks.

Orienter for Capsule-in-Capsule

Fill capsules inside capsules. Order Orienter for inner capsule size.

OE Guide Tray

All Over Encapsulation Attachments include a guide tray to correctly locate the attachment and guide the test products into the capsule.

Mixers

ProMixer

Powder Mixer/Blender

• Typical mixing time 5-10 minutes.

• Drum & V-Shells are proven designs for uniform mixing with low shear stress and no heat generation. This means minimum change in particle size distribution and no chemical degradation.

• Drum shells are lower in cost and faster and easier to use. They are filled through one opening and are self-standing.

• Traditional V-Shell requires ingredients to be charged equally through both openings. Optional stand available to free both hands for charging the V-Shell.

• Mixer & Shells made from Inox (Stainless Steel 316). Shells have mirror-finish (400 grit) and are electro-polished for extra-smooth powder flow and easy cleaning.

• Shell lids include an agitator blade to improve mixing and help break up lumps.

• PLC Control panel to set rotation speed, time and direction.

• Mixer rotation stops when safety cover opened.

Mixer Settings
Rotation Time Setting 1-60 min. Typical 5 min.
Reverse Rotation Time Setting 1 sec. to 50 min. Typical 1 min.
Rotation Speed 45 to 80 rpm.

 

Mixer Specifications
Volts / Hz. / Watts 110-230 Volts / 50-60 Hz. 40 Watts.
Weight (with 750 ml V Vessel) 12 kg (27 lbs)
L x W x H 44 x 20 x 20cm (17 x 8 x 8 inches)

  Shell Size Recommended Powder Volume Capsule Batch Size
Drum Shell 750 ml 75ml – 450ml 300 or 3 batches of 100
250 ml 25ml – 175ml 120 or 2 batches of 60
220 ml 22ml – 155ml 100 capsules
130 ml 13ml – 91ml 60 capsules

 

  Shell Size Recommended Powder Volume Capsule Batch Size
V-Shell 750 ml 75ml – 450ml 300 or 3 batches of 100
250 ml 25ml – 175ml 120 or 2 batches of 60
220 ml 22ml – 155ml 100 capsules

 

Stands free both hands when adding powder. Drum Shells are self-standing and do not require a Shell Stand.
V-Shell Stand

Molds

ProMold TTM

Tablet Triturate Molds

• For making molded tablets.

• Can also be used for making troche molds.

• 50 holes/cavities

• In three sizes: 60mg, 100mg, and 200 mg.

• Made from anodized aluminum.

• Plate size 15.2 x 7.6cm (6″ x 3″)

• Serial # marked for US DEA compliance.

Item 60mg 100mg 200mg
Hole diameter x depth 4.6 x 3.2mm 6 x 3.2mm 6 x 6.4mm
Hole diameter x depth 0.181 x 0.126 inch 0.236 x 0.126 inch 0.236 x 0.252 inch
Hole Volume ml 0.053 ml 0.090 ml 0.181 ml
Tablet Weight based on density of 0.7g/ml 0.037 g 0.063 g 0.127 g
Troche Weight based on density of 1.0g/ml 0.053 g 0.090 g 0.181 g

ProMold TLM

Troche & Lozenge Molds

Makes 100 Troches (lozenges)

Each cavity holds 725mg Polyethylene Glycol 1450. Calibrate mold with the base you are using

Custom Size Molds Available On Request

Individual Troches (Lozenges) Inches Metric
Diameter 0.48 inches 12.3 mm
Height 0.20 inches 5.0 mm
Individual Mold Hole Inches Metric
Diameter 0.5 inches 12.7 mm
Height 0.20 inches 5.0 mm
Troche & Lozenge Mold Inches Metric
Overall Length 12.5 inches 31.6 cm
Overall Width 6 inches 15.2 cm
Overall Height 0.6 inches 1.45 cm
Overall Weight 3.7 lbs 1.7 kg